Cinnamic acids and derivatives
![Medchemexpress LLC (E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-[(1S)-1-phenylethyl]prop-2-enamide | 133550-37-5 | MFCD00209855 | 97.0% | 308.33 g/mol | C18H16N2O3 | 1 ML](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000211898.png-250.jpg)
Medchemexpress LLC (E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-[(1S)-1-phenylethyl]prop-2-enamide | 133550-37-5 | MFCD00209855 | 97.0% | 308.33 g/mol | C18H16N2O3 | 1 ML
(+)-Tyrphostin B44 is the (+) enantiomer of Tyrphostin AG-835, a small-molecule inhibitor of the epidermal growth factor receptor (EGFR) used in biochemical and cellular research. It is provided as a concentrated solution in DMSO for in vitro assays and is documented with supporting datasheet, certificate of analysis, and safety data information.
- Provides EGFR inhibitory activity useful for signaling and cancer research.
- Supplied as a 10 mM solution in DMSO for ready-to-use preparations.
- High purity suitable for research applications (≈97%).
- Characterized molecular properties for accurate dosing in assays.
- Documentation available to support safe handling and experimental reproducibility.
Medchemexpress LLC Ferulic acid | 1135-24-6 | MFCD00004555 | 100.0 % | 194.18 | 25 MG
Ferulic acid (Standard) serves as the analytical standard for Ferulic acid, primarily intended for research and analytical applications. It is also recognized as a novel fibroblast growth factor receptor 1 (FGFR1) inhibitor, exhibiting IC50s of 3.78 and 12.5 μM for FGFR1 and FGFR2, respectively.
- Analytical standard for Ferulic acid
- Intended for research and analytical applications
- Novel fibroblast growth factor receptor 1 (FGFR1) inhibitor
Medchemexpress LLC Tyrphostin AG 528 | 133550-49-9 | MFCD01076474 | 98.0% | 306.32 g/mol | C18H14N2O3 | 5 MG
Tyrphostin AG 528 is a small-molecule tyrosine kinase inhibitor of EGFR and ErbB2 used in preclinical research to probe receptor signaling. It is supplied as a purified research chemical for in vitro and exploratory studies; chemical formula C18H14N2O3, molecular weight 306.32 g/mol, purity 98.0%.
- Potent inhibitor of EGFR and ErbB2 with reported IC50s of 4.9 μM and 2.1 μM.
- High purity suitable for biochemical and cellular assays.
- Available in small quantities appropriate for dose-response studies.
- Contains the CAS number 133550-49-9 for unambiguous identification.
- Supplied with a manufacturer datasheet detailing physicochemical properties and handling.
Medchemexpress LLC 2-Propenoic acid,3-(3-hydroxyphenyl)- | 588-30-7 | 100.0% | 164.16 | 100 MG
m-Coumaric acid is a polyphenol metabolite derived from caffeic acid, produced by gut microflora, and its concentration in human biofluids depends on diet. It is a BBB-penetrant metabolite of chlorogenic acid. In vitro, m-Coumaric acid stimulates cerebral nerves and can evoke neurite outgrowth in hippocampal neuronal cells, promoting neuronal differentiation.
- Increases spontaneous locomotor activity in mice
- Inhibits L-dopa oxidation by epidermis tyrosinase
- Attenuates non-catalytic protein glycosylation in retinas of diabetic rats
- Suitable for research and analytical applications
Medchemexpress LLC 4-(3-Fluorobenzyloxy)benzaldehyde | 66742-57-2 | 99.8% | C14H11FO2 | 100 G
4-(3-Fluorobenzyloxy)benzaldehyde is a chemical compound that serves as a drug intermediate. It is used in the synthesis of various active compounds for research purposes.
- Solid appearance
- Functions as a drug intermediate
- Suitable for the synthesis of active compounds
- For research use only
- Shipped at room temperature in continental US
- Store at 4°C under nitrogen
- When in solvent, store at -80°C for 6 months or -20°C for 1 month under nitrogen
Medchemexpress LLC m-Coumaric acid (Standard) | 588-30-7 | 99.91% | 164.16 | 25 MG
m-Coumaric acid (Standard) is the analytical standard of m-Coumaric acid, intended for research and analytical applications. It is a polyphenol metabolite from caffeic acid, formed by gut microflora, with its amount in human biofluids being diet-dependent. m-Coumaric acid is also a BBB-penetrant metabolite of chlorogenic acid.
- Stimulates the cerebral nerves in vitro.
- Can evoke neurite outgrowth in hippocampal neuronal cells.
- Can promote neuronal differentiation.
- Increases spontaneous locomotor activity in mice by acting on the central nervous system.
- Inhibits the oxidation of L-dopa by epidermis tyrosinase.
- Attenuates non-catalytic protein glycosylation in retinas of diabetic rats.
Medchemexpress LLC Tyrphostin AG 528 | 133550-49-9 | MFCD01076474 | 98.0% | 306.32 g·mol^-1 | C18H14N2O3 | 25 MG
Tyrphostin AG 528 is a small-molecule protein tyrosine kinase inhibitor used as a research reagent to probe EGFR and ErbB2 (HER2) signaling pathways. It is supplied as a high-purity solid for biochemical and cellular studies.
- Inhibits EGFR and ErbB2 with reported IC50s of 4.9 μM and 2.1 μM.
- High purity (98.0%) suitable for laboratory research.
- Supplied as a solid, light yellow to yellow in color.
- Molecular weight 306.32 g·mol⁻¹; formula C18H14N2O3.
- Available in small research quantities, including 25 mg packaging.
Apexbio Technology LLC (E,E)-Bisdemethoxycurcumin 33171-05-0 5mg
(E E)-Bisdemethoxycurcumin (CAS 33171-05-0) is a naturally derived curcuminoid and a structural analog within the demethoxycurcumin class Research demonstrates that this compound modulates multiple inflammatory signaling pathways and alters the expression of various inflammatory mediators It has been shown to induce cell cycle arrest promote apoptosis in cancer cells and inhibit proliferation-related pathways (E E)-Bisdemethoxycurcumin is widely utilized in studies investigating the molecular mechanisms of inflammation tumor cell biology and the pharmacological properties of curcuminoid derivatives
Medchemexpress LLC 4-(3-Fluorobenzyloxy)benzaldehyde | 66742-57-2 | 99.8% | C14H11FO2 | 10 G
4-(3-Fluorobenzyloxy)benzaldehyde is a drug intermediate for synthesis of various active compounds.
- High purity: 99.82%
- Available in various sizes
- For research use only
- Specific storage conditions: 4°C, stored under nitrogen (solid); -80°C for 6 months or -20°C for 1 month in solvent (under nitrogen)
eMolecules 537-98-4 | trans-Ferulic acid | Chem-Impex194.186 | C10H10O4 | 99.000 | COc1cc(C=CC(O)=O)ccc1O | 25g | 112756053
trans-Ferulic acid | Chem-Impex | 537-98-4194.186 | C10H10O4 | 99.000 | COc1cc(C=CC(O)=O)ccc1O | 25g | 112756053
Medchemexpress LLC 3-Methylcinnamic acid | 3029-79-6 | 99.8% | C10H10O2 | 10 G
3-Methylcinnamic acid is a drug intermediate used for the synthesis of various active compounds.
- Used as a drug intermediate
- Suitable for synthesis of various active compounds
- High purity of 99.77%